Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.73 |
| ▸ | MEN1 | O00255 | 2/20 | 0.73 |
| ▸ | F13A1 | P00488 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30148487 | 1.00 | KMT2A (0.73) | KMT2AMEN1F13A1MAPTRXFP1 | |
| SCHEMBL285046 | 1.00 | KMT2A (0.73) | KMT2AMEN1F13A1MAPTRXFP1 | |
| SCHEMBL31515175 | 0.98 | KMT2A (0.75) | KMT2AMEN1F13A1MAPTRXFP1 | |
| SCHEMBL22548403 | 0.98 | KMT2A (0.75) | KMT2AMEN1F13A1MAPTRXFP1 | |
| SCHEMBL2962696 | 0.95 | KMT2A (0.79) | KMT2AMEN1F13A1MAPTRXFP1 | |
| SCHEMBL29834154 | 0.95 | KMT2A (0.79) | KMT2AMEN1F13A1MAPTRXFP1 | |
| SCHEMBL591648 | 0.90 | KMT2A (0.91) | KMT2AMEN1F13A1MAPTRXFP1 | |
| SCHEMBL4634469 | 0.90 | KMT2A (0.91) | KMT2AMEN1F13A1MAPTRXFP1 | |
| SCHEMBL8644297 | 0.90 | KMT2A (0.91) | KMT2AMEN1F13A1MAPTRXFP1 | |
| SCHEMBL31672143 | 0.90 | KMT2A (0.91) | KMT2AMEN1F13A1MAPTRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7772402-B2 | Optically detectable organophosphonates | AUSTRIA WIRTSCHAFTSSERVICE GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (AT) | 2010-08-10 | — | — | US | disclosed |
| US-20090258422-A1 | OPTICALLY DETECTABLE ORGANOPHOSPHONATES | AUSTRIA WIRTSCHAFTSSERVICE GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (AT) | 2009-10-15 | — | — | US | disclosed |
| US-7601845-B2 | Optically detectable organophosphonates | AUSTRIA WIRTSCHAFTSSERVICE GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (AT) | 2009-10-13 | — | — | US | disclosed |
| US-20060134715-A1 | Optically detectable organophosphonates | AUSTRIA WIRTSCHAFTSSERVICE GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (AT) | 2006-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090258422-A1 | OPTICALLY DETECTABLE ORGANOPHOSPHONATES | LYPLA1, CES1, LIPE | KMT2A 4771/4885MEN1 1535/4885F13A1 1717/4885 |
| US-20060134715-A1 | Optically detectable organophosphonates | LYPLA1, CES1, LIPE | KMT2A 4771/4885MEN1 1535/4885F13A1 1717/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.