Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.83 |
| ▸ | HPGD | P15428 | 3/20 | 0.83 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.83 |
| ▸ | MEN1 | O00255 | 1/20 | 0.83 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.83 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.83 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | MPL | P40238 | 2/20 | 0.51 |
| ▸ | CDK2 | P24941 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.49 |
| ▸ | MAPK6 | Q16659 | 1/20 | 0.49 |
| ▸ | MAPKAPK5 | Q8IW41 | 1/20 | 0.49 |
| ▸ | F7 | P08709 | 1/20 | 0.46 |
| ▸ | F3 | P13726 | 1/20 | 0.46 |
| ▸ | HAT1 | O14929 | 1/20 | 0.46 |
| ▸ | EP300 | Q09472 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10253551 | 1.00 | ALDH1A1 (0.83) | ALDH1A1HPGDCYP1A2MEN1ALOX12 | |
| SCHEMBL2978109 | 0.91 | CYP1A2 (1.00) | ALDH1A1HPGDCYP1A2MEN1ALOX12 | |
| SCHEMBL1557638 | 0.89 | MEN1 (0.68) | ALDH1A1HPGDCYP1A2MEN1ALOX12 | |
| SCHEMBL2133676 | 0.87 | MEN1 (0.65) | ALDH1A1HPGDCYP1A2MEN1ALOX12 | |
| SCHEMBL29644278 | 0.87 | MEN1 (0.65) | ALDH1A1HPGDCYP1A2MEN1ALOX12 | |
| SCHEMBL3629228 | 0.87 | ALDH1A1 (0.65) | ALDH1A1HPGDCYP1A2MEN1ALOX12 | |
| SCHEMBL1465827 | 0.87 | ALDH1A1 (0.68) | ALDH1A1HPGDCYP1A2MEN1ALOX12 | |
| SCHEMBL11773319 | 0.84 | MEN1 (0.62) | ALDH1A1HPGDCYP1A2MEN1ALOX12 | |
| SCHEMBL9936837 | 0.83 | NR4A2 (0.65) | ALDH1A1HPGDCYP1A2MEN1ALOX12 | |
| SCHEMBL3174159 | 0.83 | ALDH1A1 (0.60) | ALDH1A1HPGDCYP1A2MEN1ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119306651-A | Indole 3-amide derivative and preparation method and application thereof | 山东大学 | 2025-01-14 | — | — | CN | disclosed |
| CN-116867768-A | STING antagonists and uses thereof | 上海齐鲁锐格医药研发有限公司 | 2023-10-10 | — | — | CN | disclosed |
| EP-4247790-A1 | STING ANTAGONISTS AND USES THEREOF | Qilu Regor Therapeutics Inc. (CN) | 2023-09-27 | — | — | EP | disclosed |
| WO-2022105930-A1 | STING ANTAGONISTS AND USES THEREOF | QILU REGOR THERAPEUTICS INC. (CN) | 2022-05-27 | — | — | WO | disclosed |