Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KIF11 | P52732 | 1/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 8/20 | 0.44 |
| ▸ | SCN5A | Q14524 | 7/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2141012 | 1.00 | ALDH1A1 (0.47) | ALDH1A1HPGDKDM4EHSD17B10HTT | |
| SCHEMBL10631698 | 0.90 | ALDH1A1 (0.52) | ALDH1A1HPGDKDM4EHSD17B10MEN1 | |
| SCHEMBL4943966 | 0.89 | RXRA (0.49) | HTTMEN1KMT2ASCN9ASCN5A | |
| SCHEMBL7521529 | 0.88 | HTT (0.44) | ALDH1A1HPGDKDM4EHSD17B10HTT | |
| SCHEMBL16196772 | 0.88 | KMT2A (0.50) | ALDH1A1HPGDKDM4EHSD17B10HTT | |
| SCHEMBL2137224 | 0.87 | HTT (0.64) | KDM4EHTTKIF11SCN9ASCN5A | |
| SCHEMBL29644287 | 0.87 | HTT (0.64) | KDM4EHTTKIF11SCN9ASCN5A | |
| SCHEMBL2642800 | 0.81 | ALDH1A1 (0.44) | ALDH1A1HPGDKDM4EHSD17B10MEN1 | |
| SCHEMBL10341232 | 0.80 | KDM4E (0.44) | ALDH1A1HPGDKDM4EHTTMEN1 | |
| SCHEMBL2439483 | 0.80 | IDO1 (0.49) | ALDH1A1HPGDKDM4EHSD17B10HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116867768-A | STING antagonists and uses thereof | 上海齐鲁锐格医药研发有限公司 | 2023-10-10 | — | — | CN | disclosed |
| EP-4247790-A1 | STING ANTAGONISTS AND USES THEREOF | Qilu Regor Therapeutics Inc. (CN) | 2023-09-27 | — | — | EP | disclosed |
| WO-2022105930-A1 | STING ANTAGONISTS AND USES THEREOF | QILU REGOR THERAPEUTICS INC. (CN) | 2022-05-27 | — | — | WO | disclosed |