Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1F | P30939 | 15/20 | 1.00 |
| ▸ | HTR1A | P08908 | 1/20 | 1.00 |
| ▸ | HTR1B | P28222 | 1/20 | 1.00 |
| ▸ | HTR2A | P28223 | 1/20 | 1.00 |
| ▸ | HTR2C | P28335 | 1/20 | 1.00 |
| ▸ | HTR2B | P41595 | 1/20 | 1.00 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.67 |
| ▸ | DRD5 | P21918 | 1/20 | 0.67 |
| ▸ | HTR1D | P28221 | 1/20 | 0.67 |
| ▸ | HTR1E | P28566 | 1/20 | 0.67 |
| ▸ | HTR7 | P34969 | 1/20 | 0.67 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.67 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.67 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21770793 | 1.00 | HTR1F (1.00) | HTR1FHTR1AHTR1BHTR2AHTR2C | |
| SCHEMBL21770761 | 0.89 | HTR1F (1.00) | HTR1FHTR1AHTR1BHTR2AHTR2C | |
| SCHEMBL28807271 | 0.88 | HTR1F (0.79) | HTR1FHTR1AHTR1BHTR2AHTR2C | |
| SCHEMBL21770996 | 0.87 | HTR1F (1.00) | HTR1FHTR1AHTR1BHTR2AHTR2C | |
| SCHEMBL21770760 | 0.86 | HTR1F (1.00) | HTR1FHTR1AHTR1BHTR2AHTR2C | |
| SCHEMBL21770757 | 0.85 | HTR1F (0.80) | HTR1FHTR1AHTR1BHTR2AHTR2C | |
| SCHEMBL26972708 | 0.85 | HTR1F (0.79) | HTR1FHTR1AHTR1BHTR2AHTR2C | |
| SCHEMBL21770756 | 0.85 | HTR1F (0.79) | HTR1FHTR1AHTR1BHTR2AHTR2C | |
| SCHEMBL21770995 | 0.84 | HTR1F (1.00) | HTR1FHTR1AHTR1BHTR2AHTR2C | |
| SCHEMBL29764265 | 0.84 | HTR1F (1.00) | HTR1FHTR1AHTR1BHTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4271671-A1 | SALTS OF PYRIDINYLMETHYLENEPIPERIDINE DERIVATIVES AND USES THEREOF | Sunshine Lake Pharma Co., Ltd. (CN) | 2023-11-08 | — | — | EP | disclosed |
| CN-114685445-B | Salts of pyridyleiperidine derivatives and uses thereof | 广东东阳光药业有限公司 | 2023-07-18 | — | — | CN | disclosed |
| CN-114685443-B | Salts of pyridyleiperidine derivatives and uses thereof | 广东东阳光药业有限公司 | 2023-07-18 | — | — | CN | disclosed |
| CN-114685441-B | Salts of pyridyleiperidine derivatives and uses thereof | 广东东阳光药业有限公司 | 2023-07-18 | — | — | CN | disclosed |
| CN-114685444-B | Salts of pyridyleiperidine derivatives and uses thereof | 广东东阳光药业有限公司 | 2023-07-18 | — | — | CN | disclosed |
| CN-114685440-B | Salts of pyridyleiperidine derivatives and uses thereof | 广东东阳光药业有限公司 | 2023-07-18 | — | — | CN | disclosed |
| WO-2022143622-A1 | SALTS OF PYRIDINYLMETHYLENEPIPERIDINE DERIVATIVES AND USES THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2022-07-07 | — | — | WO | disclosed |
| CN-114685443-A | Salts of pyridinylalkenylpiperidine derivatives and use thereof | 广东东阳光药业有限公司 | 2022-07-01 | — | — | CN | disclosed |
| CN-114685444-A | Salts of pyridinylalkenylpiperidine derivatives and use thereof | 广东东阳光药业有限公司 | 2022-07-01 | — | — | CN | disclosed |
| CN-114685442-A | Salts of pyridinylalkenylpiperidine derivatives and use thereof | 广东东阳光药业有限公司 | 2022-07-01 | — | — | CN | disclosed |
| CN-114685440-A | Salts of pyridinylalkenylpiperidine derivatives and use thereof | 广东东阳光药业有限公司 | 2022-07-01 | — | — | CN | disclosed |