Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1F | P30939 | 18/20 | 1.00 |
| ▸ | HTR1A | P08908 | 2/20 | 0.73 |
| ▸ | HTR1B | P28222 | 2/20 | 0.73 |
| ▸ | HTR2A | P28223 | 2/20 | 0.73 |
| ▸ | HTR2C | P28335 | 2/20 | 0.73 |
| ▸ | HTR2B | P41595 | 1/20 | 0.73 |
| ▸ | HTR1D | P28221 | 2/20 | 0.49 |
| ▸ | HTR1E | P28566 | 2/20 | 0.49 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.49 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.47 |
| ▸ | DRD5 | P21918 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29764265 | 1.00 | HTR1F (1.00) | HTR1FHTR1AHTR1BHTR2AHTR2C | |
| SCHEMBL29764248 | 0.91 | HTR1F (1.00) | HTR1FHTR1AHTR1BHTR2AHTR2C | |
| SCHEMBL21771024 | 0.91 | HTR1F (1.00) | HTR1FHTR1AHTR1BHTR2AHTR2C | |
| SCHEMBL28807272 | 0.88 | HTR1F (0.78) | HTR1FHTR1AHTR1BHTR2AHTR2C | |
| SCHEMBL21771025 | 0.87 | HTR1F (1.00) | HTR1FHTR1AHTR1BHTR2AHTR2C | |
| SCHEMBL29764278 | 0.87 | HTR1F (1.00) | HTR1FHTR1AHTR1BHTR2AHTR2C | |
| SCHEMBL21770996 | 0.85 | HTR1F (1.00) | HTR1FHTR1AHTR1BHTR2AHTR2C | |
| SCHEMBL29644497 | 0.84 | HTR1F (1.00) | HTR1FHTR1AHTR1BHTR2AHTR2C | |
| SCHEMBL21770793 | 0.84 | HTR1F (1.00) | HTR1FHTR1AHTR1BHTR2AHTR2C | |
| SCHEMBL23528939 | 0.84 | HTR1F (0.72) | HTR1FHTR1AHTR1BHTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11858910-B2 | Pyridinylmethylenepiperidine derivatives and uses thereof | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2024-01-02 | — | — | US | disclosed |
| US-11858910-B2 | Pyridinylmethylenepiperidine derivatives and uses thereof | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2024-01-02 | — | — | US | disclosed |
| US-11858910-B2 | Pyridinylmethylenepiperidine derivatives and uses thereof | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2024-01-02 | — | — | US | disclosed |
| CN-110437205-B | Pyridinonylpiperidine derivatives and use thereof | 广东东阳光药业有限公司 | 2022-07-08 | — | — | CN | disclosed |
| US-20210188803-A1 | PYRIDINYLMETHYLENEPIPERIDINE DERIVATIVES AND USES THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2021-06-24 | — | — | US | disclosed |
| US-20210188803-A1 | PYRIDINYLMETHYLENEPIPERIDINE DERIVATIVES AND USES THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2021-06-24 | — | — | US | disclosed |
| WO-2020038435-A1 | PYRIDINYLMETHYLENEPIPERIDINE DERIVATIVES AND USES THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2020-02-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11858910-B2 | Pyridinylmethylenepiperidine derivatives and uses thereof | HTR1F, HTR1A, HTR5A | HTR1F 1/4885HTR1A 2/4885HTR1B 6/4885 |
| US-20210188803-A1 | PYRIDINYLMETHYLENEPIPERIDINE DERIVATIVES AND USES THEREOF | HTR1F, HTR1A, HTR5A | HTR1F 1/4885HTR1A 2/4885HTR1B 6/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.