SCHEMBL29644532

SCHEMBL29644532

Cc1nc(NCc2ccncc2)n2nc(C)c(-c3ccc4c(c3)c(C)nn4C)c2n1

nearest known ligand 0.40

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PI4KB Q9UBF8 5/20 0.40
NAMPT P43490 7/20 0.38
CRHR1 P34998 4/20 0.35
ALDH1A1 P00352 2/20 0.34
RXFP1 Q9HBX9 1/20 0.34
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.33
HPGD P15428 1/20 0.33
HTT P42858 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21628170 1.00 PI4KB (0.40) PI4KBNAMPTCRHR1ALDH1A1RXFP1
SCHEMBL20528839 0.89 CRHR1 (0.42) PI4KBCRHR1ALDH1A1MAPTHPGD
SCHEMBL29644481 0.88 MAPT (0.45) CRHR1ALDH1A1MAPT
SCHEMBL20529340 0.88 MAPT (0.45) CRHR1ALDH1A1MAPT
SCHEMBL23395419 0.88 LMNA (0.39) PI4KBCRHR1ALDH1A1RXFP1LMNA
SCHEMBL23387094 0.87 PI4KB (0.38) PI4KBCRHR1RXFP1MAPT
SCHEMBL21628157 0.86 PI4KB (0.46) PI4KBMAPT
SCHEMBL29644514 0.86 PI4KB (0.46) PI4KBMAPT
SCHEMBL20528851 0.86 CRHR1 (0.39) PI4KBCRHR1ALDH1A1RXFP1MAPT
SCHEMBL29644519 0.86 CRHR1 (0.39) PI4KBCRHR1ALDH1A1RXFP1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4676485-A1 COMPOUND AND FORMULATION FOR SYSTEMIC THERAPY BY ORAL TRANSMUCOSAL ADMINISTRATION CUROVIR AB (SE) 2026-01-14 EP claimed
WO-2024184442-A1 COMPOUND AND FORMULATION FOR SYSTEMIC THERAPY BY ORAL TRANSMUCOSAL ADMINISTRATION CUROVIR AB (SE) 2024-09-12 WO claimed
EP-4028131-A1 HETEROAROMATIC COMPOUNDS USEFUL IN THERAPY CUROVIR AB (SE) 2022-07-20 EP claimed
CN-110520424-B Heteroaromatic compounds for therapy 库洛维公司 2022-06-21 CN claimed
EP-4676485-A1 COMPOUND AND FORMULATION FOR SYSTEMIC THERAPY BY ORAL TRANSMUCOSAL ADMINISTRATION CUROVIR AB (SE) 2026-01-14 EP disclosed
WO-2024184442-A1 COMPOUND AND FORMULATION FOR SYSTEMIC THERAPY BY ORAL TRANSMUCOSAL ADMINISTRATION CUROVIR AB (SE) 2024-09-12 WO disclosed