Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLA1 | P09884 | 1/20 | 0.52 |
| ▸ | CYP46A1 | Q9Y6A2 | 2/20 | 0.51 |
| ▸ | ST6GAL1 | P15907 | 7/20 | 0.49 |
| ▸ | ST3GAL1 | Q11201 | 2/20 | 0.49 |
| ▸ | ST3GAL3 | Q11203 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.47 |
| ▸ | OSBP | P22059 | 1/20 | 0.47 |
| ▸ | RORC | P51449 | 1/20 | 0.47 |
| ▸ | OSBP2 | Q969R2 | 1/20 | 0.47 |
| ▸ | NPC1L1 | Q9UHC9 | 2/20 | 0.46 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | GBA1 | P04062 | 2/20 | 0.44 |
| ▸ | UGCG | Q16739 | 2/20 | 0.44 |
| ▸ | GBA2 | Q9HCG7 | 2/20 | 0.44 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30475052 | 0.88 | CYP46A1 (0.54) | POLA1CYP46A1ST6GAL1ST3GAL1ST3GAL3 | |
| SCHEMBL31430017 | 0.88 | CYP46A1 (0.54) | POLA1CYP46A1ST6GAL1ST3GAL1ST3GAL3 | |
| SCHEMBL11948053 | 0.84 | POLA1 (0.65) | POLA1CYP46A1USP2LMNAABCB1 | |
| SCHEMBL15702066 | 0.84 | POLA1 (0.65) | POLA1CYP46A1USP2LMNAABCB1 | |
| SCHEMBL15702062 | 0.83 | POLA1 (0.65) | POLA1CYP46A1USP2LMNAABCB1 | |
| SCHEMBL16883325 | 0.83 | POLA1 (0.65) | POLA1CYP46A1USP2LMNAABCB1 | |
| SCHEMBL26032453 | 0.83 | POLA1 (0.65) | POLA1CYP46A1USP2LMNAABCB1 | |
| SCHEMBL15674814 | 0.83 | POLA1 (0.67) | POLA1CYP46A1USP2LMNAABCB1 | |
| SCHEMBL19486134 | 0.83 | POLA1 (0.67) | POLA1CYP46A1USP2LMNAABCB1 | |
| SCHEMBL2334975 | 0.82 | POLA1 (0.64) | POLA1CYP46A1USP2LMNAABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12502354-B2 | High density lipoprotein mimetic nanoparticles using lipid conjugated core scaffolds | NORTHWESTERN UNIVERSITY (US) | 2025-12-23 | — | — | US | disclosed |
| US-20250177301-A1 | TRIPLEX NANOPARTICLES | UNM RAINFOREST INNOVATIONS | 2025-06-05 | — | — | US | disclosed |
| WO-2023147596-A1 | TRIPLEX NANOPARTICLES | NOUREDDINE ACHRAF (US) | 2023-08-03 | — | — | WO | disclosed |
| EP-4056205-A1 | MICRO-RNA COMPOSITION FUNCTIONALIZED FOR DENTAL IMPLANTS | Vilnius University Hospital Zalgiris Clinic (LT) | 2022-09-14 | — | — | EP | disclosed |
| US-20220151928-A1 | HIGH DENSITY LIPOPROTEIN MIMETIC NANOPARTICLES USING LIPID CONJUGATED CORE SCAFFOLDS | NORTHWESTERN UNIVERSITY (US) | 2022-05-19 | — | — | US | disclosed |