Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP46A1 | Q9Y6A2 | 2/20 | 0.54 |
| ▸ | POLA1 | P09884 | 1/20 | 0.53 |
| ▸ | ST6GAL1 | P15907 | 3/20 | 0.51 |
| ▸ | ST3GAL1 | Q11201 | 2/20 | 0.51 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.51 |
| ▸ | ST3GAL3 | Q11203 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.48 |
| ▸ | OSBP | P22059 | 1/20 | 0.48 |
| ▸ | RORC | P51449 | 1/20 | 0.48 |
| ▸ | OSBP2 | Q969R2 | 1/20 | 0.48 |
| ▸ | NPC1L1 | Q9UHC9 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.46 |
| ▸ | GBA1 | P04062 | 1/20 | 0.45 |
| ▸ | UGCG | Q16739 | 1/20 | 0.45 |
| ▸ | GBA2 | Q9HCG7 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31430017 | 1.00 | CYP46A1 (0.54) | CYP46A1POLA1ST6GAL1ST3GAL1PLA2G2A | |
| SCHEMBL4142848 | 0.89 | POLA1 (0.54) | CYP46A1POLA1ST6GAL1ST3GAL1PLA2G2A | |
| SCHEMBL29644556 | 0.88 | POLA1 (0.52) | CYP46A1POLA1ST6GAL1ST3GAL1PLA2G2A | |
| SCHEMBL1956603 | 0.87 | OSBP (0.47) | CYP46A1POLA1ST6GAL1ST3GAL1ST3GAL3 | |
| SCHEMBL13311383 | 0.87 | OSBP (0.47) | CYP46A1POLA1ST6GAL1ST3GAL1ST3GAL3 | |
| SCHEMBL12639020 | 0.87 | CYP46A1 (0.47) | CYP46A1POLA1ST6GAL1ST3GAL1ST3GAL3 | |
| SCHEMBL12639016 | 0.87 | OSBP (0.47) | CYP46A1POLA1ST6GAL1ST3GAL1ST3GAL3 | |
| SCHEMBL13311391 | 0.87 | CYP46A1 (0.47) | CYP46A1POLA1ST6GAL1ST3GAL1ST3GAL3 | |
| SCHEMBL1878894 | 0.87 | CYP46A1 (0.47) | CYP46A1POLA1ST6GAL1ST3GAL1ST3GAL3 | |
| SCHEMBL1956604 | 0.87 | OSBP (0.47) | CYP46A1POLA1ST6GAL1ST3GAL1ST3GAL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4469058-A1 | ANTI-PARASITE COMPOUNDS | Australian National University (AU) | 2024-12-04 | — | — | EP | disclosed |
| WO-2023137529-A1 | ANTI-PARASITE COMPOUNDS | AUSTRALIAN NATIONAL UNIVERSITY (AU) | 2023-07-27 | — | — | WO | disclosed |