Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.65 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | FES | P07332 | 1/20 | 0.51 |
| ▸ | RET | P07949 | 1/20 | 0.51 |
| ▸ | MARK3 | P27448 | 1/20 | 0.51 |
| ▸ | TYK2 | P29597 | 1/20 | 0.51 |
| ▸ | FLT4 | P35916 | 1/20 | 0.51 |
| ▸ | SYK | P43405 | 1/20 | 0.51 |
| ▸ | CLK2 | P49760 | 1/20 | 0.51 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1815219 | 1.00 | RECQL (0.66) | RECQLCYP1A2CYP2D6CHRM2ALDH1A1 | |
| SCHEMBL2006175 | 0.85 | CYP1A2 (0.67) | RECQLCYP1A2CYP2D6CHRM2ALDH1A1 | |
| SCHEMBL29653592 | 0.85 | CYP1A2 (0.67) | RECQLCYP1A2CYP2D6CHRM2ALDH1A1 | |
| SCHEMBL3398316 | 0.85 | CYP1A2 (0.67) | RECQLCYP1A2CYP2D6CHRM2ALDH1A1 | |
| SCHEMBL4462447 | 0.84 | RECQL (0.54) | RECQLCYP1A2CYP2D6CYP3A4CYP2C9 | |
| SCHEMBL14189533 | 0.83 | CYP1A2 (0.65) | RECQLCYP1A2CYP2D6CHRM2ALDH1A1 | |
| SCHEMBL423358 | 0.82 | CYP1A2 (0.62) | RECQLCYP1A2CYP2D6CHRM2ALDH1A1 | |
| SCHEMBL2861457 | 0.80 | CYP1A2 (1.00) | RECQLCYP1A2CYP2D6CHRM2ALDH1A1 | |
| SCHEMBL24996969 | 0.80 | CYP1A2 (0.59) | RECQLCYP1A2CYP2D6CHRM2ALDH1A1 | |
| SCHEMBL13154263 | 0.80 | CYP1A2 (0.59) | RECQLCYP1A2CYP2D6CHRM2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220135547-A1 | HETEROCYCLIC LOW-MOLECULAR SAPP MIMETICS, A PHARMACEUTICAL COMPOSITION AND METHODS FOR PRODUCING AND USING SAME | NENAYDENOV VALENTIN G (RU) | 2022-05-05 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220135547-A1 | HETEROCYCLIC LOW-MOLECULAR SAPP MIMETICS, A PHARMACEUTICAL COMPOSITION AND METHODS FOR PRODUCING AND USING SAME | APP, IAPP, BDNF | RECQL 2477/4885CYP1A2 4806/4885CYP2D6 4873/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.