Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Mycophenolic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 known ✓ | P12268 | 20/20 | 1.00 |
| ▸ | IMPDH1 known ✓ | P20839 | 10/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 1.00 |
| ▸ | LMNA | P02545 | 1/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 1/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 1/20 | 1.00 |
| ▸ | HPGD | P15428 | 1/20 | 1.00 |
| ▸ | UGT2B7 | P16662 | 1/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 1.00 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.79 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.79 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.79 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.79 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.79 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.79 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.79 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.79 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Mycophenolic Acid SCHEMBL1657813 | 1.00 | IMPDH2 (1.00) | IMPDH2IMPDH1KDM4EALDH1A1LMNA | |
| Mycophenolic Acid SCHEMBL2514376 | 1.00 | IMPDH2 (1.00) | IMPDH2IMPDH1KDM4EALDH1A1LMNA | |
| Mycophenolic Acid SCHEMBL29380425 | 1.00 | IMPDH2 (1.00) | IMPDH2IMPDH1KDM4EALDH1A1LMNA | |
| Mycophenolic Acid SCHEMBL4549 | 1.00 | IMPDH2 (1.00) | IMPDH2IMPDH1KDM4EALDH1A1LMNA | |
| Mycophenolic Acid SCHEMBL5259872 | 1.00 | IMPDH2 (1.00) | IMPDH2IMPDH1KDM4EALDH1A1LMNA | |
| Mycophenolic Acid SCHEMBL5500098 | 1.00 | IMPDH2 (1.00) | IMPDH2IMPDH1KDM4EALDH1A1LMNA | |
| Mycophenolic Acid SCHEMBL1230249 | 1.00 | IMPDH2 (1.00) | IMPDH2IMPDH1KDM4EALDH1A1LMNA | |
| Mycophenolic Acid SCHEMBL6502425 | 0.99 | IMPDH2 (0.98) | IMPDH2IMPDH1KDM4EALDH1A1LMNA | |
| Mycophenolic Acid SCHEMBL3652377 | 0.99 | IMPDH2 (0.98) | IMPDH2IMPDH1KDM4EALDH1A1LMNA | |
| Mycophenolic Acid SCHEMBL1657815 | 0.99 | IMPDH2 (0.98) | IMPDH2IMPDH1KDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025064458-A1 | PREVENTION AND TREATMENT OF VIRAL INFECTIONS | BARANOWITZ STEVEN (US) | 2025-03-27 | — | — | WO | disclosed |
| CN-118812355-A | Preparation method of diene ester compound | 华南理工大学 | 2024-10-22 | — | — | CN | disclosed |
| WO-2023150067-A1 | PHARMACEUTICAL COMPOSITIONS AND METHODS FOR TREATING COVID | BARANOWITZ STEVEN (US) | 2023-08-10 | — | — | WO | disclosed |
| WO-2023014518-A1 | PHARMACEUTICAL COMPOSITIONS AND METHODS FOR TREATING NEOPLASIA | BARANOWITZ STEVEN (US) | 2023-02-09 | — | — | WO | disclosed |
| CN-114689725-A | Detection method of mycophenolic acid and impurities thereof | 鲁南制药集团股份有限公司 | 2022-07-01 | — | — | CN | disclosed |