SCHEMBL29645145

SCHEMBL29645145

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nearest known ligand 0.46

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 11/20 0.46
BACE2 Q9Y5Z0 2/20 0.46
CTSD P07339 2/20 0.44
FNTA P49354 2/20 0.43
FNTB P49356 2/20 0.43
CTSB P07858 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30837136 0.84 BACE1 (0.53) BACE1BACE2CTSD
SCHEMBL31182817 0.84 OPRD1 (0.46)
SCHEMBL30392483 0.84 MME (0.44)
SCHEMBL29714714 0.84 FNTA (0.48) BACE1CTSDFNTAFNTB
SCHEMBL29892499 0.83 FOLH1 (0.50) FNTAFNTB
SCHEMBL30997370 0.83 OPRM1 (0.48) BACE1BACE2
SCHEMBL30011199 0.83 FNTA (0.48) BACE1BACE2CTSDFNTAFNTB
SCHEMBL30011243 0.83 FNTA (0.48) BACE1BACE2CTSDFNTAFNTB
SCHEMBL30010811 0.83 FNTA (0.48) BACE1BACE2CTSDFNTAFNTB
SCHEMBL30010590 0.83 FNTA (0.48) BACE1BACE2CTSDFNTAFNTB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220175955-A1 PEPTIDE DISPLAY TO ANTIGEN PRESENTING CELLS USING LIPID VEHICLE DANMARKS TEKNISKE UNIVERSITET (DK) 2022-06-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220175955-A1 PEPTIDE DISPLAY TO ANTIGEN PRESENTING CELLS USING LIPID VEHICLE CD74, MICA, TAP1 BACE1 1603/4885BACE2 1265/4885CTSD 232/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.