Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK1 | Q13464 | 12/20 | 0.69 |
| ▸ | BCL6 | P41182 | 1/20 | 0.69 |
| ▸ | CA12 | O43570 | 1/20 | 0.62 |
| ▸ | CA1 | P00915 | 1/20 | 0.62 |
| ▸ | CA2 | P00918 | 1/20 | 0.62 |
| ▸ | CA6 | P23280 | 1/20 | 0.62 |
| ▸ | CA5A | P35218 | 1/20 | 0.62 |
| ▸ | CA7 | P43166 | 1/20 | 0.62 |
| ▸ | CA9 | Q16790 | 1/20 | 0.62 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.62 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.62 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.59 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.54 |
| ▸ | HTR3B | O95264 | 1/20 | 0.54 |
| ▸ | HTR3A | P46098 | 1/20 | 0.54 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.54 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.54 |
| ▸ | CDC7 | O00311 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31337029 | 0.82 | SCN9A (0.82) | ROCK1BCL6CA12CA1CA2 | |
| SCHEMBL31336991 | 0.82 | ROCK1 (0.69) | ROCK1BCL6CA12CA1CA2 | |
| SCHEMBL13963140 | 0.82 | ROCK1 (0.69) | ROCK1BCL6CA12CA1CA2 | |
| SCHEMBL31337079 | 0.82 | ROCK1 (0.69) | ROCK1BCL6CA12CA1CA2 | |
| SCHEMBL1193264 | 0.81 | ROCK1 (1.00) | ROCK1BCL6CA12CA1CA2 | |
| SCHEMBL12968741 | 0.81 | ROCK1 (1.00) | ROCK1BCL6CA12CA1CA2 | |
| SCHEMBL270349 | 0.81 | RAB9A (0.69) | ROCK1BCL6CA12CA1CA2 | |
| SCHEMBL12968977 | 0.81 | ROCK1 (0.63) | ROCK1BCL6CA12CA1CA2 | |
| SCHEMBL29645155 | 0.80 | ROCK1 (0.68) | ROCK1BCL6HTR3EHTR3BHTR3A | |
| SCHEMBL2410497 | 0.79 | RAB9A (0.62) | CA12CA1CA2CA9RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119080704-A | Rosin acid derivative and preparation method and application thereof | 广东药科大学 | 2024-12-06 | — | — | CN | disclosed |
| US-11739072-B2 | Heteroaryl compounds and their use | MINORYX THERAPEUTICS S.L. (ES) | 2023-08-29 | — | — | US | disclosed |
| US-20220135535-A1 | HETEROARYL COMPOUNDS AND THEIR USE | MINORYX THERAPEUTICS S.L. (ES) | 2022-05-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220135535-A1 | HETEROARYL COMPOUNDS AND THEIR USE | GBA1, GBA2, GAA | ROCK1 3651/4885BCL6 2335/4885CA12 4431/4885 |
| US-11739072-B2 | Heteroaryl compounds and their use | GBA1, GBA2, GAA | ROCK1 3651/4885BCL6 2335/4885CA12 4431/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.