Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK1 | Q13464 | 12/20 | 0.68 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.68 |
| ▸ | HTR3B | O95264 | 1/20 | 0.68 |
| ▸ | HTR3A | P46098 | 1/20 | 0.68 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.68 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.68 |
| ▸ | BCL6 | P41182 | 1/20 | 0.66 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.59 |
| ▸ | PRKACA | P17612 | 1/20 | 0.59 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.59 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.59 |
| ▸ | CDC42BPA | Q5VT25 | 1/20 | 0.59 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.53 |
| ▸ | CDC7 | O00311 | 1/20 | 0.52 |
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.51 |
| ▸ | EGFR | P00533 | 2/20 | 0.51 |
| ▸ | ITK | Q08881 | 1/20 | 0.51 |
| ▸ | JAK2 | O60674 | 1/20 | 0.50 |
| ▸ | JAK3 | P52333 | 1/20 | 0.50 |
| ▸ | AURKA | O14965 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13166084 | 0.81 | TNNI3K (0.63) | ROCK1ROCK2PRKACAPRKCDDYRK1A | |
| SCHEMBL27612768 | 0.81 | SYK (0.70) | ROCK1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL13166085 | 0.81 | NFKB1 (0.58) | ROCK1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL12813346 | 0.81 | ROCK1 (1.00) | ROCK1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL12968972 | 0.81 | ROCK1 (1.00) | ROCK1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL29645150 | 0.80 | ROCK1 (0.69) | ROCK1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL1193264 | 0.80 | ROCK1 (1.00) | ROCK1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL15305716 | 0.79 | RAB9A (0.55) | ROCK1EGFR | |
| SCHEMBL28212946 | 0.79 | TNNI3K (0.54) | TNNI3KEGFR | |
| SCHEMBL20355745 | 0.79 | CYP1A2 (0.73) | ROCK2EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119080704-A | Rosin acid derivative and preparation method and application thereof | 广东药科大学 | 2024-12-06 | — | — | CN | disclosed |
| US-11739072-B2 | Heteroaryl compounds and their use | MINORYX THERAPEUTICS S.L. (ES) | 2023-08-29 | — | — | US | disclosed |
| US-20220135535-A1 | HETEROARYL COMPOUNDS AND THEIR USE | MINORYX THERAPEUTICS S.L. (ES) | 2022-05-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220135535-A1 | HETEROARYL COMPOUNDS AND THEIR USE | GBA1, GBA2, GAA | ROCK1 3651/4885HTR3E 2048/4885HTR3B 1236/4885 |
| US-11739072-B2 | Heteroaryl compounds and their use | GBA1, GBA2, GAA | ROCK1 3651/4885HTR3E 2048/4885HTR3B 1236/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.