SCHEMBL29645164

SCHEMBL29645164

C=Cc1ccc(COC2CC(C)(C)NC(C)(C)C2)cc1

nearest known ligand 0.35

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.35
EZH2 Q15910 1/20 0.35
ALDH1A1 P00352 3/20 0.34
NPSR1 Q6W5P4 1/20 0.34
KDM4E B2RXH2 2/20 0.33
LMNA P02545 1/20 0.33
SLC2A1 P11166 1/20 0.32
MEN1 O00255 1/20 0.32
POLB P06746 1/20 0.32
MAPT P10636 1/20 0.32
RECQL P46063 1/20 0.32
KMT2A Q03164 1/20 0.32
OPRM1 P35372 2/20 0.31
OPRL1 P41146 2/20 0.31
NAAA Q02083 1/20 0.31
BCHE P06276 1/20 0.30
KDM1A O60341 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL565118 0.87 GAA (0.42) GAAEZH2ALDH1A1NPSR1KDM4E
SCHEMBL19845816 0.83 NAAA (0.43) GAAEZH2ALDH1A1NPSR1KDM4E
SCHEMBL2514086 0.81 NAAA (0.46) GAAEZH2ALDH1A1NPSR1KDM4E
SCHEMBL17075343 0.80 MEN1 (0.34) ALDH1A1MEN1POLBMAPTKMT2A
SCHEMBL17075344 0.80 GAA (0.38) GAAALDH1A1MEN1KMT2AOPRM1
SCHEMBL451933 0.80 GAA (0.50) GAAEZH2ALDH1A1KDM4ELMNA
SCHEMBL24246793 0.79 NAAA (0.35) MEN1KMT2ANAAA
SCHEMBL9456407 0.77 KDM4E (0.55) GAAEZH2ALDH1A1NPSR1KDM4E
SCHEMBL22154463 0.76 GAA (0.33) GAAMEN1KMT2A
SCHEMBL9674783 0.74 GAA (0.40) GAAEZH2ALDH1A1KDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110536926-B Method for preparing a heterophasic polymer composition 美利肯公司 2022-05-31 CN disclosed
US-20220153974-A1 Modified Heterophasic Polyolefin Composition MILLIKEN & COMPANY 2022-05-19 US disclosed