SCHEMBL24246793

SCHEMBL24246793

C=Cc1ccc(COC2CC(C)(C)N(OC)C(C)(C)C2)cc1

nearest known ligand 0.35

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 15/20 0.35
CTSL P07711 1/20 0.32
CTSB P07858 1/20 0.32
CTSK P43235 1/20 0.32
KMT2A Q03164 2/20 0.31
MEN1 O00255 1/20 0.31
TSHR P16473 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17075343 0.85 MEN1 (0.34) NAAACTSLCTSBCTSKKMT2A
SCHEMBL17075344 0.85 GAA (0.38) NAAACTSLCTSBCTSKKMT2A
SCHEMBL22154463 0.81 GAA (0.33) KMT2AMEN1
SCHEMBL29645164 0.79 GAA (0.35) NAAAKMT2AMEN1
SCHEMBL7476490 0.74 CARM1 (0.36) NAAACTSLCTSBCTSKKMT2A
SCHEMBL9003678 0.73 POLB (0.45) KMT2AMEN1TSHR
SCHEMBL9003582 0.72 HTT (0.36) KMT2AMEN1TSHR
SCHEMBL7475314 0.71 CARM1 (0.45) NAAACTSLCTSBCTSKKMT2A
SCHEMBL7931906 0.71 EPHX2 (0.31)
SCHEMBL7478962 0.71 GAA (0.44) NAAACTSLCTSBCTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11248114-B2 Modified heterophasic polyolefin composition MILLIKEN & COMPANY (US) 2022-02-15 US disclosed