Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.34 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.34 |
| ▸ | EP300 | Q09472 | 1/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.33 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31413362 | 0.84 | KDM4C (0.35) | KDM4CSLC6A9EP300CREBBPMAPT | |
| SCHEMBL21107455 | 0.83 | SLCO1B1 (0.40) | KDM4CSLC6A9EP300CREBBPMAPT | |
| SCHEMBL29869865 | 0.83 | SLCO1B1 (0.35) | KDM4CSLC6A9EP300CREBBPMAPT | |
| SCHEMBL21107344 | 0.83 | SLCO1B1 (0.35) | KDM4CSLC6A9EP300CREBBPMAPT | |
| SCHEMBL22467484 | 0.80 | SLCO1B1 (0.37) | KDM4CCREBBPKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL29634339 | 0.80 | SLCO1B1 (0.37) | KDM4CCREBBPKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL21107815 | 0.78 | SLCO1B1 (0.37) | KDM4CSLC6A9CREBBPKMT2AMEN1 | |
| SCHEMBL29868781 | 0.76 | KDM4C (0.34) | KDM4CKMT2AMEN1HPGDNPC1 | |
| SCHEMBL21107114 | 0.76 | KDM4C (0.34) | KDM4CKMT2AMEN1HPGDNPC1 | |
| SCHEMBL24555903 | 0.74 | SLCO1B1 (0.49) | KDM4CSLC6A9MAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112074515-B | Cyclic compounds as LPA antagonists isoxazoles of hexyl acid | 百时美施贵宝公司 | 2025-01-10 | — | — | CN | disclosed |
| CN-114599640-A | Isoxazole carboxylic acids as LPA antagonists | 百时美施贵宝公司 | 2022-06-07 | — | — | CN | disclosed |
| CN-114599641-A | Cyclobutylcarboxylic acids as LPA antagonists | 百时美施贵宝公司 | 2022-06-07 | — | — | CN | disclosed |