SCHEMBL2964538

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2957759	0.88	MTNR1A (0.60)	PTGDR2MTNR1AMTNR1BCA1CA2
	SCHEMBL2957111	0.84	PTGDR2 (0.47)	PTGDR2CA1CA2CA9CA12
	SCHEMBL2968543	0.79	MTNR1A (0.44)	PTGDR2MTNR1AMTNR1BCA1CA2
	SCHEMBL1208094	0.79	HTR2C (0.55)	PTGDR2MEN1KMT2AGAAFFAR1
	SCHEMBL2134746	0.78	FFAR1 (0.47)	MTNR1AMTNR1BNPSR1MEN1KMT2A
	SCHEMBL2962486	0.78	FFAR1 (0.47)	MTNR1AMTNR1BNPSR1MEN1KMT2A
	SCHEMBL21921670	0.78	FFAR1 (0.47)	MTNR1AMTNR1BNPSR1MEN1KMT2A
	SCHEMBL2134742	0.78	FFAR1 (0.47)	MTNR1AMTNR1BNPSR1MEN1KMT2A
	SCHEMBL14480439	0.75	FFAR1 (0.47)	KMT2AFFAR1
	SCHEMBL2133690	0.75	FFAR1 (0.47)	KMT2AFFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.