Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.41 |
| ▸ | PRKDC | P78527 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29645656 | 0.88 | PIK3CA (0.44) | PIK3CAALDH1A1KDM4EMAPTPIK3CD | |
| SCHEMBL29645574 | 0.84 | KDM4E (0.48) | ALDH1A1KDM4EPOLBMAPTTHRB | |
| SCHEMBL29645741 | 0.84 | KDM4E (0.48) | ALDH1A1KDM4EPOLBMAPTTHRB | |
| SCHEMBL29645940 | 0.84 | KDM4E (0.43) | ALDH1A1KDM4EPOLBMAPTTHRB | |
| SCHEMBL29645839 | 0.83 | KDM4E (0.47) | ALDH1A1KDM4EPOLBMAPTTHRB | |
| SCHEMBL29645929 | 0.83 | KDM4E (0.47) | ALDH1A1KDM4EPOLBMAPTTHRB | |
| SCHEMBL29646008 | 0.83 | KDM4E (0.47) | ALDH1A1KDM4EPOLBMAPTTHRB | |
| SCHEMBL29645699 | 0.83 | KDM4E (0.47) | ALDH1A1KDM4EPOLBMAPTTHRB | |
| SCHEMBL29645803 | 0.82 | POLB (0.46) | ALDH1A1KDM4EPOLBMAPTTHRB | |
| SCHEMBL29646501 | 0.82 | KDM4E (0.46) | ALDH1A1KDM4EPOLBMAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | claimed |
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | disclosed |