Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C1R | P00736 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 8/20 | 0.38 |
| ▸ | THRB | P10828 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.36 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | ADK | P55263 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29645596 | 0.93 | C1R (0.39) | C1RMAPTTHRBTP53SMN1; SMN2 | |
| SCHEMBL29646039 | 0.92 | C1R (0.40) | C1RMAPTTHRBTP53SMN1; SMN2 | |
| SCHEMBL29645620 | 0.92 | MAPT (0.36) | C1RMAPTTHRBTP53SMN1; SMN2 | |
| SCHEMBL29645621 | 0.90 | C1R (0.37) | C1RMAPTTHRBTP53SMN1; SMN2 | |
| SCHEMBL29645546 | 0.90 | MAPT (0.38) | C1RMAPTTHRBTP53SMN1; SMN2 | |
| SCHEMBL29645715 | 0.89 | MAPT (0.39) | C1RMAPTTHRBTP53POLB | |
| SCHEMBL29645518 | 0.89 | C1R (0.38) | C1RMAPTTHRBTP53SMN1; SMN2 | |
| SCHEMBL29646060 | 0.89 | TP53 (0.47) | C1RMAPTTHRBTP53SMN1; SMN2 | |
| SCHEMBL29645792 | 0.87 | MAPT (0.38) | MAPTTHRBTP53SMN1; SMN2POLB | |
| SCHEMBL29646134 | 0.87 | CYP1A2 (0.42) | C1RMAPTTP53POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466850-B | [1,2,4] Triazolo [1,5-C ] quinazolin-5-amine | 拜耳股份有限公司 | 2024-09-10 | — | — | CN | claimed |
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | claimed |