Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | ADK | P55263 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29645568 | 0.89 | MAPT (0.35) | MAPTTP53P2RX7POLBTHRB | |
| SCHEMBL29645931 | 0.89 | MAPT (0.39) | MAPTTP53P2RX7POLBADORA3 | |
| SCHEMBL29646060 | 0.89 | TP53 (0.47) | MAPTTP53POLBMEN1KMT2A | |
| SCHEMBL29645620 | 0.88 | MAPT (0.36) | MAPTTP53POLBTHRBSMN1; SMN2 | |
| SCHEMBL29645459 | 0.87 | C1R (0.43) | MAPTTP53POLBTHRBSMN1; SMN2 | |
| SCHEMBL29646028 | 0.86 | MAPT (0.45) | MAPTTP53POLBKMT2ATHRB | |
| SCHEMBL29645527 | 0.85 | MAPT (0.41) | MAPTTP53POLBADK | |
| SCHEMBL29645608 | 0.84 | MAPT (0.40) | MAPTTP53POLBKMT2ATHRB | |
| SCHEMBL29645636 | 0.83 | MAPT (0.47) | MAPTPOLBMEN1KMT2ATHRB | |
| SCHEMBL29645843 | 0.83 | KMT2A (0.44) | MAPTTP53POLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466850-B | [1,2,4] Triazolo [1,5-C ] quinazolin-5-amine | 拜耳股份有限公司 | 2024-09-10 | — | — | CN | claimed |
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | claimed |