Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C1R | P00736 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 7/20 | 0.39 |
| ▸ | TP53 | P04637 | 4/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.33 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29646039 | 0.94 | C1R (0.40) | C1RMAPTTP53RXFP1THRB | |
| SCHEMBL29645459 | 0.93 | C1R (0.43) | C1RMAPTTP53RXFP1THRB | |
| SCHEMBL29645621 | 0.91 | C1R (0.37) | C1RMAPTTP53RXFP1THRB | |
| SCHEMBL29645546 | 0.91 | MAPT (0.38) | C1RMAPTTP53THRBSMN1; SMN2 | |
| SCHEMBL29645674 | 0.87 | MAPT (0.41) | MAPTTP53RXFP1ADORA3POLB | |
| SCHEMBL29645715 | 0.86 | MAPT (0.39) | C1RMAPTTP53THRBADORA3 | |
| SCHEMBL29645518 | 0.86 | C1R (0.38) | C1RMAPTTP53THRBSMN1; SMN2 | |
| SCHEMBL29645620 | 0.85 | MAPT (0.36) | C1RMAPTTP53RXFP1THRB | |
| SCHEMBL29645642 | 0.85 | MAPT (0.43) | C1RMAPTTP53RXFP1THRB | |
| SCHEMBL29645702 | 0.85 | MAPT (0.41) | MAPTTP53RXFP1ADORA3POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466850-B | [1,2,4] Triazolo [1,5-C ] quinazolin-5-amine | 拜耳股份有限公司 | 2024-09-10 | — | — | CN | claimed |
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | claimed |