Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 16/20 | 0.34 |
| ▸ | CCNA2 | P20248 | 5/20 | 0.32 |
| ▸ | CDK2 | P24941 | 5/20 | 0.32 |
| ▸ | CCNA1 | P78396 | 5/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | CDK7 | P50613 | 1/20 | 0.31 |
| ▸ | CCNH | P51946 | 1/20 | 0.31 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.31 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22988465 | 1.00 | CHEK1 (0.34) | CHEK1CCNA2CDK2CCNA1IRAK4 | |
| SCHEMBL22979421 | 0.92 | ADORA3 (0.33) | CHEK1CCNA2CDK2CCNA1IRAK4 | |
| SCHEMBL29645870 | 0.92 | ADORA3 (0.33) | CHEK1CCNA2CDK2CCNA1IRAK4 | |
| SCHEMBL22988287 | 0.90 | CHEK1 (0.33) | CHEK1CCNA2CDK2CCNA1IRAK4 | |
| SCHEMBL22988168 | 0.90 | ADORA2A (0.34) | CHEK1CCNA2CDK2CCNA1IRAK4 | |
| SCHEMBL29648608 | 0.90 | ADORA2A (0.34) | CHEK1CCNA2CDK2CCNA1IRAK4 | |
| SCHEMBL22988253 | 0.87 | ADORA3 (0.35) | CHEK1CCNA2CDK2CCNA1IRAK4 | |
| SCHEMBL22979234 | 0.87 | AURKB (0.32) | — | |
| SCHEMBL22988283 | 0.87 | KDM4E (0.42) | ADORA3ADORA2AADORA1 | |
| SCHEMBL29645506 | 0.87 | KDM4E (0.42) | ADORA3ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4013508-A1 | [1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINES | Bayer Aktiengesellschaft (DE) | 2022-06-22 | — | — | EP | claimed |
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | claimed |