Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 7/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 7/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 7/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 5/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 7/20 | 0.33 |
| ▸ | RPLP1 | P05386 | 1/20 | 0.32 |
| ▸ | RPLP0 | P05388 | 1/20 | 0.32 |
| ▸ | RPS17 | P08708 | 1/20 | 0.32 |
| ▸ | RPSA | P08865 | 1/20 | 0.32 |
| ▸ | RPS2 | P15880 | 1/20 | 0.32 |
| ▸ | RPL35A | P18077 | 1/20 | 0.32 |
| ▸ | RPL7 | P18124 | 1/20 | 0.32 |
| ▸ | RPL17 | P18621 | 1/20 | 0.32 |
| ▸ | RPS4Y1 | P22090 | 1/20 | 0.32 |
| ▸ | RPS3 | P23396 | 1/20 | 0.32 |
| ▸ | RPS12 | P25398 | 1/20 | 0.32 |
| ▸ | RPL13 | P26373 | 1/20 | 0.32 |
| ▸ | RPL10 | P27635 | 1/20 | 0.32 |
| ▸ | RPL12 | P30050 | 1/20 | 0.32 |
| ▸ | RPL9; RPL9P7; RPL9P8; RPL9P9 | P32969 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29645870 | 1.00 | ADORA3 (0.33) | ADORA3ADORA2AADORA1ADORA2BCHEK1 | |
| SCHEMBL22988287 | 0.92 | CHEK1 (0.33) | ADORA3ADORA2AADORA1ADORA2BCHEK1 | |
| SCHEMBL22988465 | 0.92 | CHEK1 (0.34) | ADORA3ADORA2AADORA1ADORA2BCHEK1 | |
| SCHEMBL29645472 | 0.92 | CHEK1 (0.34) | ADORA3ADORA2AADORA1ADORA2BCHEK1 | |
| SCHEMBL29645784 | 0.92 | AURKB (0.32) | — | |
| SCHEMBL22979234 | 0.92 | AURKB (0.32) | — | |
| SCHEMBL22979719 | 0.89 | ADORA2A (0.36) | ADORA3ADORA2AADORA1ADORA2BIRAK4 | |
| SCHEMBL29646119 | 0.89 | ADORA2A (0.36) | ADORA3ADORA2AADORA1ADORA2BIRAK4 | |
| SCHEMBL22988253 | 0.89 | ADORA3 (0.35) | ADORA3ADORA2AADORA1ADORA2BCHEK1 | |
| SCHEMBL22987891 | 0.88 | RPLP1 (0.34) | ADORA3ADORA2AADORA1ADORA2BCHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4013508-A1 | [1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINES | Bayer Aktiengesellschaft (DE) | 2022-06-22 | — | — | EP | claimed |
| WO-2021028382-A1 | [1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINES | BAYER AKTIENGESELLSCHAFT (DE) | 2021-02-18 | — | — | WO | claimed |
| US-20230113037-A1 | [1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINES | BAYER AKTIENGESELLSCHAFT (DE) | 2023-04-13 | — | — | US | disclosed |
| WO-2021028382-A1 | [1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINES | BAYER AKTIENGESELLSCHAFT (DE) | 2021-02-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230113037-A1 | [1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINES | AHR, HRH4, HRH1 | ADORA3 34/4885ADORA2A 103/4885ADORA1 21/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.