Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 9/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | CASP1 | P29466 | 2/20 | 0.34 |
| ▸ | CASP7 | P55210 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29645567 | 0.94 | MAPT (0.41) | PDE10AMAPTTHRBADORA3ALDH1A1 | |
| SCHEMBL29646084 | 0.93 | MAPT (0.40) | PDE10AMAPTTHRBPIK3CAMAPK8 | |
| SCHEMBL29645545 | 0.89 | MAPT (0.40) | MAPTTHRBADORA3ALDH1A1KDM4E | |
| SCHEMBL29645656 | 0.85 | PIK3CA (0.44) | MAPTTHRBPIK3CAALDH1A1KDM4E | |
| SCHEMBL29645660 | 0.84 | MAPT (0.44) | MAPTTHRBADORA3ALDH1A1KDM4E | |
| SCHEMBL29645863 | 0.84 | MAPT (0.44) | MAPTTHRBADORA3ALDH1A1KDM4E | |
| SCHEMBL29645468 | 0.83 | MAPT (0.44) | MAPTTHRBADORA3ALDH1A1KDM4E | |
| SCHEMBL29645991 | 0.83 | MAPT (0.44) | MAPTTHRBADORA3ALDH1A1KDM4E | |
| SCHEMBL29645910 | 0.82 | KDM4E (0.44) | MAPTTHRBADORA3ALDH1A1KDM4E | |
| SCHEMBL29645603 | 0.81 | MAPT (0.46) | MAPTTHRBADORA3ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | claimed |
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | disclosed |