Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 4/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.36 |
| ▸ | CASP1 | P29466 | 4/20 | 0.36 |
| ▸ | CASP7 | P55210 | 4/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29645530 | 0.94 | PDE10A (0.42) | MAPTTHRBADORA3ALDH1A1KDM4E | |
| SCHEMBL29646084 | 0.94 | MAPT (0.40) | MAPTTHRBADORA3ALDH1A1KDM4E | |
| SCHEMBL29645545 | 0.93 | MAPT (0.40) | MAPTTHRBADORA3ALDH1A1KDM4E | |
| SCHEMBL29645863 | 0.87 | MAPT (0.44) | MAPTTHRBADORA3ALDH1A1KDM4E | |
| SCHEMBL29645660 | 0.87 | MAPT (0.44) | MAPTTHRBADORA3ALDH1A1KDM4E | |
| SCHEMBL29645910 | 0.87 | KDM4E (0.44) | MAPTTHRBADORA3ALDH1A1KDM4E | |
| SCHEMBL29645991 | 0.86 | MAPT (0.44) | MAPTTHRBADORA3ALDH1A1KDM4E | |
| SCHEMBL29645468 | 0.86 | MAPT (0.44) | MAPTTHRBADORA3ALDH1A1KDM4E | |
| SCHEMBL29645744 | 0.84 | MAPT (0.36) | MAPTCYP1A2CYP3A4PDE10A | |
| SCHEMBL29645487 | 0.83 | MAPT (0.59) | MAPTTHRBADORA3ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | claimed |