Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31149890 | 0.91 | THRB (0.43) | MAPTPOLBLMNATP53NPC1 | |
| SCHEMBL29645950 | 0.90 | MAPT (0.41) | MAPTPOLBLMNATP53NPC1 | |
| SCHEMBL29645743 | 0.88 | GRM2 (0.39) | MAPTPOLBLMNATP53NPC1 | |
| SCHEMBL29645430 | 0.88 | NPC1 (0.48) | MAPTPOLBTP53NPC1RAB9A | |
| SCHEMBL29645527 | 0.88 | MAPT (0.41) | MAPTPOLBLMNATP53ADK | |
| SCHEMBL29645843 | 0.88 | KMT2A (0.44) | MAPTPOLBTP53NPSR1ALDH1A1 | |
| SCHEMBL29645636 | 0.88 | MAPT (0.47) | MAPTPOLBLMNACYP1A2CYP3A4 | |
| SCHEMBL29645894 | 0.87 | KDM1A (0.40) | MAPTPOLBTP53ALDH1A1ADORA3 | |
| SCHEMBL29646208 | 0.87 | MAPT (0.41) | MAPTPOLBTP53ALDH1A1RXFP1 | |
| SCHEMBL29645608 | 0.87 | MAPT (0.40) | MAPTPOLBTP53SMN1; SMN2ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | claimed |