Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 5/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 9/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 8/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 7/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 5/20 | 0.34 |
| ▸ | IRAK1 | P51617 | 3/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 4/20 | 0.33 |
| ▸ | RPLP1 | P05386 | 1/20 | 0.33 |
| ▸ | RPLP0 | P05388 | 1/20 | 0.33 |
| ▸ | RPS17 | P08708 | 1/20 | 0.33 |
| ▸ | RPSA | P08865 | 1/20 | 0.33 |
| ▸ | RPS2 | P15880 | 1/20 | 0.33 |
| ▸ | RPL35A | P18077 | 1/20 | 0.33 |
| ▸ | RPL7 | P18124 | 1/20 | 0.33 |
| ▸ | RPL17 | P18621 | 1/20 | 0.33 |
| ▸ | RPS4Y1 | P22090 | 1/20 | 0.33 |
| ▸ | RPS3 | P23396 | 1/20 | 0.33 |
| ▸ | RPS12 | P25398 | 1/20 | 0.33 |
| ▸ | RPL13 | P26373 | 1/20 | 0.33 |
| ▸ | RPL10 | P27635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22978977 | 1.00 | IRAK4 (0.34) | IRAK4ADORA3ADORA1ADORA2AADORA2B | |
| SCHEMBL29645907 | 0.91 | JAK2 (0.34) | — | |
| SCHEMBL22979336 | 0.91 | JAK2 (0.34) | — | |
| SCHEMBL22988253 | 0.91 | ADORA3 (0.35) | IRAK4ADORA3ADORA1ADORA2AADORA2B | |
| SCHEMBL22988486 | 0.91 | PIM1 (0.34) | ADORA2BCDK2 | |
| SCHEMBL22988396 | 0.91 | CCNK (0.38) | IRAK4ADORA3ADORA1ADORA2AADORA2B | |
| SCHEMBL29645793 | 0.91 | CCNK (0.38) | IRAK4ADORA3ADORA1ADORA2AADORA2B | |
| SCHEMBL22987861 | 0.90 | ADORA3 (0.34) | IRAK4ADORA3ADORA1ADORA2AADORA2B | |
| SCHEMBL22987891 | 0.90 | RPLP1 (0.34) | IRAK4ADORA3ADORA1ADORA2AADORA2B | |
| SCHEMBL22988299 | 0.90 | ADORA3 (0.34) | IRAK4ADORA3ADORA1ADORA2AADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4013508-A1 | [1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINES | Bayer Aktiengesellschaft (DE) | 2022-06-22 | — | — | EP | claimed |
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | claimed |