Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | XPO1 | O14980 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | MAT2A | P31153 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31150073 | 0.91 | CYP1A2 (0.37) | MAPTCYP1A2CYP3A4EGFRPDE10A | |
| SCHEMBL29645511 | 0.86 | ADORA3 (0.41) | MAPTCYP1A2CYP3A4PDE10ACSNK1D | |
| SCHEMBL29645787 | 0.86 | MAPT (0.38) | MAPTPDE10ACSNK1DLMNARXFP1 | |
| SCHEMBL29645499 | 0.84 | MAPT (0.37) | MAPTPDE10ACSNK1DLMNARXFP1 | |
| SCHEMBL29645567 | 0.84 | MAPT (0.41) | MAPTCYP1A2CYP3A4PDE10A | |
| SCHEMBL29645458 | 0.84 | MAPT (0.50) | MAPTRXFP1TP53 | |
| SCHEMBL22979322 | 0.79 | KDM4E (0.39) | MAPTCYP1A2CYP3A4PDE10ALMNA | |
| SCHEMBL31149867 | 0.79 | KDM4E (0.39) | MAPTCYP1A2CYP3A4PDE10ALMNA | |
| SCHEMBL22979365 | 0.78 | PLAT (0.34) | MAPTCYP1A2CYP3A4EGFRPDE10A | |
| SCHEMBL22979634 | 0.78 | PLAT (0.34) | MAPTCYP1A2CYP3A4EGFRPDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | claimed |