Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 3/20 | 0.39 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 5/20 | 0.38 |
| ▸ | DHODH | Q02127 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CASP1 | P29466 | 2/20 | 0.37 |
| ▸ | CASP7 | P55210 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29645542 | 0.90 | MAPT (0.46) | MAPTSMN1; SMN2DYRK1ACLK4THRB | |
| SCHEMBL29646003 | 0.88 | MAPT (0.56) | MAPTSMN1; SMN2DYRK1ACLK4THRB | |
| SCHEMBL29645822 | 0.85 | MAPT (0.47) | MAPTSMN1; SMN2DYRK1ACLK4THRB | |
| SCHEMBL29646058 | 0.85 | MAPT (0.47) | MAPTSMN1; SMN2THRBABCG2KMT2A | |
| SCHEMBL29645544 | 0.83 | MAPT (0.53) | MAPTSMN1; SMN2THRBLMNAKMT2A | |
| SCHEMBL29645482 | 0.83 | MAPT (0.53) | MAPTSMN1; SMN2DYRK1ACLK4THRB | |
| SCHEMBL29646166 | 0.82 | PIK3CD (0.35) | — | |
| SCHEMBL29645863 | 0.81 | MAPT (0.44) | MAPTSMN1; SMN2CLK4THRBLMNA | |
| SCHEMBL29645660 | 0.81 | MAPT (0.44) | MAPTSMN1; SMN2CLK4THRBLMNA | |
| SCHEMBL31150055 | 0.81 | MAPT (0.44) | MAPTSMN1; SMN2DYRK1ACLK4THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | claimed |