Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 4/20 | 0.34 |
| ▸ | EGFR | P00533 | 7/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | TYK2 | P29597 | 1/20 | 0.33 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.33 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.33 |
| ▸ | CDK2 | P24941 | 2/20 | 0.33 |
| ▸ | CDK9 | P50750 | 2/20 | 0.33 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.33 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.33 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29645724 | 0.90 | AXL (0.34) | METEGFRMAPK8MAPK10KDM1A | |
| SCHEMBL29645501 | 0.90 | EGFR (0.33) | METEGFRMAPK8MAPK10KDM1A | |
| SCHEMBL29646031 | 0.89 | KDR (0.33) | AURKBADORA2AADORA1METEGFR | |
| SCHEMBL29645782 | 0.86 | MAPT (0.43) | ADORA2AADORA1KDM1A | |
| SCHEMBL29646046 | 0.86 | ADORA1 (0.36) | AURKBADORA2AADORA2BADORA1MET | |
| SCHEMBL29645944 | 0.84 | EGFR (0.33) | METEGFR | |
| SCHEMBL29645874 | 0.83 | ADORA3 (0.40) | ADORA2AADORA2BADORA1METKDM1A | |
| SCHEMBL29645635 | 0.82 | MAPT (0.44) | — | |
| SCHEMBL31149882 | 0.81 | MAPT (0.38) | ADORA2AADORA1CCNT1CCNE2CCNE1 | |
| SCHEMBL31149965 | 0.81 | KDR (0.33) | AURKBADORA2AADORA1METEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | claimed |