Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 7/20 | 0.37 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | XDH | P47989 | 1/20 | 0.34 |
| ▸ | FPR2 | P25090 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | PRKCI | P41743 | 1/20 | 0.32 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29645934 | 1.00 | ADORA3 (0.37) | ADORA3DGAT2ADORA2AADORA1MAPT | |
| SCHEMBL29645526 | 1.00 | ADORA3 (0.37) | ADORA3DGAT2ADORA2AADORA1MAPT | |
| SCHEMBL22980999 | 1.00 | ADORA3 (0.37) | ADORA3DGAT2ADORA2AADORA1MAPT | |
| SCHEMBL22979466 | 1.00 | ADORA3 (0.37) | ADORA3DGAT2ADORA2AADORA1MAPT | |
| SCHEMBL22988284 | 0.92 | ADORA3 (0.37) | ADORA3DGAT2ADORA2AADORA1MAPT | |
| SCHEMBL29645978 | 0.92 | ADORA3 (0.37) | ADORA3DGAT2ADORA2AADORA1MAPT | |
| SCHEMBL22988343 | 0.90 | XDH (0.34) | ADORA3ADORA2AADORA1MAPTXDH | |
| SCHEMBL22979383 | 0.90 | XDH (0.34) | ADORA3ADORA2AADORA1MAPTXDH | |
| SCHEMBL29645550 | 0.90 | XDH (0.34) | ADORA3ADORA2AADORA1MAPTXDH | |
| SCHEMBL22979905 | 0.89 | MAPT (0.39) | ADORA3ADORA2AADORA1MAPTXDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4013508-A1 | [1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINES | Bayer Aktiengesellschaft (DE) | 2022-06-22 | — | — | EP | claimed |
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | claimed |
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | disclosed |