SCHEMBL2964575

SCHEMBL2964575

CC1=CCc2cc(Br)cc(C)c21

nearest known ligand 0.37

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.37
ALDH1A1 P00352 1/20 0.37
MAPT P10636 1/20 0.37
KMT2A Q03164 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
HTR1D P28221 1/20 0.32
HTR1B P28222 1/20 0.32
GABRA1 P14867 1/20 0.30
GABRB1 P18505 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2963510 0.82 MEN1 (0.41) MEN1ALDH1A1MAPTKMT2ASMN1; SMN2
SCHEMBL2975302 0.73 CHEK1 (0.32)
SCHEMBL2963377 0.73 AKR1C3 (0.37) MEN1ALDH1A1MAPTKMT2ASMN1; SMN2
SCHEMBL2964358 0.73 ALDH1A1 (0.43) MEN1ALDH1A1MAPTKMT2ASMN1; SMN2
SCHEMBL8749812 0.73 TAS1R3 (0.32) HTR1DHTR1B
SCHEMBL12159414 0.71 NQO2 (0.38) ALDH1A1HTR1DHTR1BGABRA1GABRB1
SCHEMBL2968083 0.71 MEN1 (0.40) MEN1ALDH1A1MAPTKMT2ASMN1; SMN2
SCHEMBL2958716 0.71 MEN1 (0.48) MEN1ALDH1A1MAPTKMT2ASMN1; SMN2
SCHEMBL2965107 0.69 MEN1 (0.30) MEN1ALDH1A1MAPTKMT2ASMN1; SMN2
SCHEMBL2973074 0.68 MEN1 (0.34) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7763562-B2 Heteroatom bridged metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2010-07-27 US disclosed
US-20070135597-A1 Heteroatom bridged metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. 2007-06-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070135597-A1 Heteroatom bridged metallocene compounds for olefin polymerization AP2M1, AP1M1, PYM1 MEN1 750/4885ALDH1A1 4332/4885MAPT 206/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.