Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29645568 | 0.90 | MAPT (0.35) | MAPTPOLBTP53ADORA3P2RX7 | |
| SCHEMBL29645792 | 0.89 | MAPT (0.38) | MAPTPOLBTP53ADORA3P2RX7 | |
| SCHEMBL29645715 | 0.88 | MAPT (0.39) | MAPTPOLBTP53ADORA3LMNA | |
| SCHEMBL29645564 | 0.88 | P2RX7 (0.37) | ADORA3P2RX7 | |
| SCHEMBL29645469 | 0.86 | P2RX7 (0.36) | P2RX7 | |
| SCHEMBL29645546 | 0.84 | MAPT (0.38) | MAPTPOLBTP53ADORA3 | |
| SCHEMBL29646028 | 0.81 | MAPT (0.45) | MAPTPOLBTP53ADORA3LMNA | |
| SCHEMBL29645888 | 0.81 | MAPT (0.55) | MAPTPOLBTP53ADORA3LMNA | |
| SCHEMBL29645636 | 0.81 | MAPT (0.47) | MAPTPOLBADORA3LMNA | |
| SCHEMBL29646060 | 0.80 | TP53 (0.47) | MAPTPOLBTP53ADORA3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466850-B | [1,2,4] Triazolo [1,5-C ] quinazolin-5-amine | 拜耳股份有限公司 | 2024-09-10 | — | — | CN | claimed |
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | claimed |