Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 1/20 | 0.31 |
| ▸ | CCNK | O75909 | 1/20 | 0.31 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | CDK9 | P50750 | 1/20 | 0.31 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.30 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22979211 | 1.00 | CCNT1 (0.31) | CCNT1CCNKCCNE1CDK2CDK9 | |
| SCHEMBL22988368 | 0.90 | ADORA2A (0.34) | ADORA3ADORA2AADORA1 | |
| SCHEMBL29648636 | 0.90 | ADORA2A (0.34) | ADORA3ADORA2AADORA1 | |
| SCHEMBL22980681 | 0.89 | ADORA2A (0.33) | ADORA3ADORA2AADORA1 | |
| SCHEMBL29645639 | 0.89 | ADORA2A (0.33) | ADORA3ADORA2AADORA1 | |
| SCHEMBL22988490 | 0.88 | CCNT1 (0.31) | CCNT1CCNKCCNE1CDK2CDK9 | |
| SCHEMBL22980897 | 0.88 | CCNT1 (0.31) | CCNT1CCNKCCNE1CDK2CDK9 | |
| SCHEMBL22988295 | 0.83 | USP30 (0.33) | ADORA3ADORA2AADORA1 | |
| SCHEMBL30393564 | 0.83 | USP30 (0.33) | ADORA3ADORA2AADORA1 | |
| SCHEMBL22979421 | 0.82 | ADORA3 (0.33) | CDK2ADORA3ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4013508-A1 | [1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINES | Bayer Aktiengesellschaft (DE) | 2022-06-22 | — | — | EP | claimed |
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | claimed |