Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.33 |
| ▸ | XDH | P47989 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | FPR2 | P25090 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 3/20 | 0.30 |
| ▸ | HTR2B | P41595 | 3/20 | 0.30 |
| ▸ | HTR2A | P28223 | 2/20 | 0.30 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.30 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.30 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.30 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22987909 | 1.00 | ADORA3 (0.33) | ADORA3ADORA1XDHMAPTFPR2 | |
| SCHEMBL22988384 | 0.93 | PLAT (0.34) | MAPTSCN9APDE10A | |
| SCHEMBL29645847 | 0.93 | PLAT (0.34) | MAPTSCN9APDE10A | |
| SCHEMBL22988281 | 0.91 | MAPT (0.37) | ADORA3ADORA1XDHMAPT | |
| SCHEMBL29645425 | 0.91 | MAPT (0.37) | ADORA3ADORA1XDHMAPT | |
| SCHEMBL29648555 | 0.89 | ADORA1 (0.40) | ADORA3ADORA1XDHMAPTFPR2 | |
| SCHEMBL22980234 | 0.89 | ADORA1 (0.40) | ADORA3ADORA1XDHMAPTFPR2 | |
| SCHEMBL22988343 | 0.88 | XDH (0.34) | ADORA3ADORA1XDHMAPTFPR2 | |
| SCHEMBL22980999 | 0.88 | ADORA3 (0.37) | ADORA3ADORA1XDHMAPTFPR2 | |
| SCHEMBL22979383 | 0.88 | XDH (0.34) | ADORA3ADORA1XDHMAPTFPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4013508-A1 | [1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINES | Bayer Aktiengesellschaft (DE) | 2022-06-22 | — | — | EP | claimed |
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | claimed |