Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 2/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 8/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 2/20 | 0.31 |
| ▸ | TTK | P33981 | 2/20 | 0.31 |
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE1A | P54750 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.31 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29645875 | 0.88 | AXL (0.37) | METADORA3ADORA1ADORA2ABRD4 | |
| SCHEMBL29646046 | 0.86 | ADORA1 (0.36) | METADORA3ADORA1ADORA2ABRD4 | |
| SCHEMBL29645810 | 0.86 | ADORA3 (0.35) | METADORA3ADORA1ADORA2ABRD4 | |
| SCHEMBL29645761 | 0.85 | ROS1 (0.34) | ADORA3ADORA1ADORA2ABRD4 | |
| SCHEMBL29645939 | 0.85 | KDM4E (0.44) | ADORA3ADORA1ADORA2A | |
| SCHEMBL29646040 | 0.85 | JAK2 (0.31) | METTTK | |
| SCHEMBL29645614 | 0.84 | TTK (0.39) | ADORA3ADORA1ADORA2ABRD4TTK | |
| SCHEMBL29645800 | 0.84 | CHEK1 (0.34) | ADORA3ADORA1ADORA2ABRD4TTK | |
| SCHEMBL29646062 | 0.83 | ADORA3 (0.34) | ADORA3ADORA1ADORA2ABRD4EGFR | |
| SCHEMBL29645782 | 0.83 | MAPT (0.43) | ADORA3ADORA1ADORA2AKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466850-B | [1,2,4] Triazolo [1,5-C ] quinazolin-5-amine | 拜耳股份有限公司 | 2024-09-10 | — | — | CN | claimed |
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | claimed |