Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 1/20 | 0.37 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 8/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.33 |
| ▸ | MET | P08581 | 2/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | USP1 | O94782 | 2/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29646046 | 0.88 | ADORA1 (0.36) | AXLADORA3ADORA1ADORA2AMET | |
| SCHEMBL29645810 | 0.88 | ADORA3 (0.35) | ADORA3ADORA1ADORA2AMETBRD4 | |
| SCHEMBL29646019 | 0.88 | MET (0.33) | ADORA3ADORA1ADORA2AMETBRD4 | |
| SCHEMBL29645761 | 0.87 | ROS1 (0.34) | ADORA3ADORA1ADORA2ABRD4 | |
| SCHEMBL29645614 | 0.86 | TTK (0.39) | AXLJAK1JAK3ADORA3ADORA1 | |
| SCHEMBL29645800 | 0.86 | CHEK1 (0.34) | ADORA3ADORA1ADORA2ABRD4KDM1A | |
| SCHEMBL29646062 | 0.85 | ADORA3 (0.34) | ADORA3ADORA1ADORA2ABRD4 | |
| SCHEMBL29645782 | 0.85 | MAPT (0.43) | ADORA3ADORA1ADORA2AKDM1A | |
| SCHEMBL29645725 | 0.84 | TP53 (0.35) | AXLADORA3ADORA1ADORA2AMET | |
| SCHEMBL29646158 | 0.84 | ADORA3 (0.32) | ADORA3ADORA1ADORA2AMETBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | claimed |