Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 4/20 | 0.38 |
| ▸ | GNAO1 | P09471 | 4/20 | 0.38 |
| ▸ | GNAI1 | P63096 | 4/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | DRD5 | P21918 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | GLB1 | P16278 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29646150 | 1.00 | GNAI3 (0.38) | GNAI3GNAO1GNAI1HTR1ADRD2 | |
| SCHEMBL29646215 | 0.90 | HRH3 (0.37) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL29646161 | 0.90 | HRH3 (0.37) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL18013068 | 0.83 | ESR1 (0.31) | — | |
| SCHEMBL25005192 | 0.82 | HRH3 (0.35) | — | |
| SCHEMBL19123527 | 0.82 | HRH3 (0.35) | — | |
| SCHEMBL28192983 | 0.80 | DRD2 (0.43) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL19888519 | 0.79 | — | — | |
| SCHEMBL12912029 | 0.79 | GNAI3 (0.42) | GNAI3GNAO1GNAI1HTR1ADRD2 | |
| SCHEMBL14749186 | 0.79 | GNAI3 (0.42) | GNAI3GNAO1GNAI1HTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022059684-A1 | VITAMIN D DERIVATIVE HAVING CYCLIC AMINE IN SIDE CHAIN | 帝人ファーマ株式会社 | 2022-03-24 | — | — | WO | disclosed |