Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | GBA1 | P04062 | 1/20 | 0.32 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 2/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18885236 | 1.00 | GAA (0.33) | GAAGBA1KCNJ1KCNH2HTR1A | |
| SCHEMBL27281638 | 1.00 | GAA (0.33) | GAAGBA1KCNJ1KCNH2HTR1A | |
| SCHEMBL30598324 | 0.87 | GBA2 (0.37) | GAAGBA1 | |
| SCHEMBL30598291 | 0.87 | GBA2 (0.37) | GAAGBA1 | |
| SCHEMBL12568602 | 0.84 | SIGMAR1 (0.39) | — | |
| SCHEMBL18912360 | 0.84 | SIGMAR1 (0.39) | — | |
| SCHEMBL81698 | 0.84 | SIGMAR1 (0.39) | — | |
| SCHEMBL11739122 | 0.84 | EBP (0.43) | GAAGBA1 | |
| SCHEMBL11738374 | 0.84 | EBP (0.43) | GAAGBA1 | |
| SCHEMBL9801097 | 0.80 | KCNJ1 (0.42) | KCNJ1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023171736-A1 | MEDICINE CONTAINING VITAMIN D DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT OR SOLVATE THEREOF, USED IN COMBINATION WITH IMMUNOMODULATORY SUBSTANCE | 帝人ファーマ株式会社 | 2023-09-14 | — | — | WO | disclosed |
| WO-2022059684-A1 | VITAMIN D DERIVATIVE HAVING CYCLIC AMINE IN SIDE CHAIN | 帝人ファーマ株式会社 | 2022-03-24 | — | — | WO | disclosed |