Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ1 | P48048 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | DRD5 | P21918 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9801551 | 0.89 | SIGMAR1 (0.46) | KCNJ1KCNH2SIGMAR1CYP2D6CYP2C19 | |
| SCHEMBL9801966 | 0.88 | MAPK1 (0.47) | KCNJ1KCNH2SIGMAR1CYP2D6CYP2C19 | |
| SCHEMBL9801487 | 0.88 | ALOX15 (0.43) | KCNJ1KCNH2SIGMAR1CYP2D6CYP2C19 | |
| SCHEMBL13550395 | 0.88 | MAPK1 (0.44) | KCNJ1KCNH2SIGMAR1CYP2D6CYP2C19 | |
| SCHEMBL9801364 | 0.85 | SIGMAR1 (0.41) | KCNJ1KCNH2SIGMAR1 | |
| SCHEMBL9801938 | 0.85 | KCNJ1 (0.37) | KCNJ1KCNH2SIGMAR1CYP2D6 | |
| SCHEMBL23267012 | 0.81 | SIGMAR1 (0.37) | KCNJ1KCNH2SIGMAR1CYP2D6CYP2C19 | |
| SCHEMBL23205217 | 0.81 | SIGMAR1 (0.40) | KCNJ1KCNH2SIGMAR1 | |
| SCHEMBL9801956 | 0.80 | DRD2 (0.41) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL11957693 | 0.80 | DRD2 (0.41) | DRD2DRD1DRD4DRD5DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008028427-A1 | DERIVATIVES OF 2-PHENYL-3-HYDROXYQUINOLINE-4(1H)-ONE AND METHODS OF THEIR PREPARATION AND UTILIZATION | UNIVERZITA PALACKEHO (CZ) | 2008-03-13 | — | — | WO | disclosed |
| US-4992150-A | Telomer with alpha-olefin;oil and fuel additive | NIPPON OIL CO, LTD. (JP) | 1991-02-12 | — | — | US | disclosed |