Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | THRB | P10828 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.57 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22980034 | 1.00 | RXFP1 (0.61) | RXFP1TP53THRBMAPTADORA3 | |
| SCHEMBL29646467 | 0.87 | ADORA3 (0.56) | RXFP1TP53MAPTADORA3ADORA1 | |
| SCHEMBL22979446 | 0.87 | ADORA3 (0.56) | RXFP1TP53MAPTADORA3ADORA1 | |
| SCHEMBL22979023 | 0.86 | ADORA3 (0.69) | TP53THRBMAPTADORA3ADORA1 | |
| SCHEMBL29646414 | 0.86 | ADORA3 (0.69) | TP53THRBMAPTADORA3ADORA1 | |
| SCHEMBL29646504 | 0.85 | ADORA3 (0.64) | RXFP1TP53MAPTADORA3ADORA1 | |
| SCHEMBL22979475 | 0.85 | ADORA3 (0.64) | RXFP1TP53MAPTADORA3ADORA1 | |
| SCHEMBL22988116 | 0.85 | ADORA3 (0.53) | RXFP1TP53THRBMAPTADORA3 | |
| SCHEMBL22979532 | 0.85 | ADORA3 (0.53) | RXFP1TP53THRBMAPTADORA3 | |
| SCHEMBL29646353 | 0.85 | ADORA3 (0.53) | RXFP1TP53THRBMAPTADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466850-B | [1,2,4] Triazolo [1,5-C ] quinazolin-5-amine | 拜耳股份有限公司 | 2024-09-10 | — | — | CN | disclosed |
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | disclosed |