Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.40 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | XDH | P47989 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22980130 | 1.00 | RXFP1 (0.44) | RXFP1MAPTLMNATHRBKDM4E | |
| SCHEMBL22988148 | 0.90 | MAPT (0.41) | RXFP1MAPTLMNAKDM4EALDH1A1 | |
| SCHEMBL22987904 | 0.88 | AMY1A (0.43) | RXFP1MAPTLMNAKDM4EALDH1A1 | |
| SCHEMBL22988024 | 0.87 | TP53 (0.46) | MAPTTP53PDE10AXDH | |
| SCHEMBL22987505 | 0.86 | NR1H2 (0.41) | RXFP1MAPTLMNAKDM4EALDH1A1 | |
| SCHEMBL22979532 | 0.84 | ADORA3 (0.53) | RXFP1MAPTTHRBTP53 | |
| SCHEMBL29646353 | 0.84 | ADORA3 (0.53) | RXFP1MAPTTHRBTP53 | |
| SCHEMBL22987536 | 0.81 | AMY1A (0.44) | RXFP1MAPTLMNAKDM4EALDH1A1 | |
| SCHEMBL22987462 | 0.80 | KDM4E (0.50) | MAPTTHRBKDM4EALDH1A1TP53 | |
| SCHEMBL22987463 | 0.79 | ADORA3 (0.39) | THRBTP53PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466850-B | [1,2,4] Triazolo [1,5-C ] quinazolin-5-amine | 拜耳股份有限公司 | 2024-09-10 | — | — | CN | disclosed |
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | disclosed |