Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | XDH | P47989 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22987398 | 1.00 | HPGD (0.51) | HPGDALDH1A1XDHADORA3ADORA1 | |
| SCHEMBL22987933 | 0.92 | ADORA3 (0.47) | HPGDALDH1A1XDHADORA3ADORA1 | |
| SCHEMBL29646428 | 0.86 | ADORA3 (0.50) | HPGDALDH1A1ADORA3ADORA1MAPT | |
| SCHEMBL22980067 | 0.86 | TP53 (0.47) | ADORA3ADORA1MAPTMAPK1TP53 | |
| SCHEMBL22979102 | 0.86 | ADORA3 (0.50) | HPGDALDH1A1ADORA3ADORA1MAPT | |
| SCHEMBL29646419 | 0.86 | TP53 (0.47) | ADORA3ADORA1MAPTMAPK1TP53 | |
| SCHEMBL22987617 | 0.86 | NPC1 (0.58) | HPGDALDH1A1ADORA3ADORA1MAPT | |
| SCHEMBL22987555 | 0.84 | ADORA3 (0.43) | HPGDXDHADORA3ADORA1MAPT | |
| SCHEMBL22979023 | 0.83 | ADORA3 (0.69) | ADORA3ADORA1MAPTMEN1KMT2A | |
| SCHEMBL29646414 | 0.83 | ADORA3 (0.69) | ADORA3ADORA1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466850-B | [1,2,4] Triazolo [1,5-C ] quinazolin-5-amine | 拜耳股份有限公司 | 2024-09-10 | — | — | CN | disclosed |
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | disclosed |