Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | GBA1 | P04062 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22980067 | 1.00 | TP53 (0.47) | TP53ADORA3ADORA1HIF1AGBA1 | |
| SCHEMBL22987561 | 0.87 | DHODH (0.40) | TP53ADORA3MAPT | |
| SCHEMBL22987554 | 0.87 | ADORA3 (0.43) | TP53ADORA3ADORA1MAPTADORA2A | |
| SCHEMBL22987930 | 0.87 | ADORA3 (0.43) | TP53ADORA3ADORA1MAPT | |
| SCHEMBL22987556 | 0.86 | RXFP1 (0.43) | TP53ADORA3ADORA1MAPTPOLB | |
| SCHEMBL22987398 | 0.86 | HPGD (0.51) | TP53ADORA3ADORA1MAPTADORA2A | |
| SCHEMBL29646409 | 0.86 | HPGD (0.51) | TP53ADORA3ADORA1MAPTADORA2A | |
| SCHEMBL22987933 | 0.83 | ADORA3 (0.47) | ADORA3ADORA1MAPT | |
| SCHEMBL22987617 | 0.83 | NPC1 (0.58) | ADORA3ADORA1MAPT | |
| SCHEMBL22979102 | 0.83 | ADORA3 (0.50) | ADORA3ADORA1MAPTADORA2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466850-B | [1,2,4] Triazolo [1,5-C ] quinazolin-5-amine | 拜耳股份有限公司 | 2024-09-10 | — | — | CN | disclosed |
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | disclosed |