Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.34 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.34 |
| ▸ | TRPC7 | Q9HCX4 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | GPR39 | O43194 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 3/20 | 0.33 |
| ▸ | JAK1 | P23458 | 3/20 | 0.33 |
| ▸ | TYK2 | P29597 | 2/20 | 0.33 |
| ▸ | JAK3 | P52333 | 2/20 | 0.33 |
| ▸ | PARP1 | P09874 | 2/20 | 0.33 |
| ▸ | TNKS | O95271 | 1/20 | 0.33 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.33 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22987521 | 1.00 | ADORA3 (0.35) | ADORA3ADORA1ADORA2AUSP30TRPC3 | |
| SCHEMBL22988275 | 0.93 | USP30 (0.34) | ADORA3ADORA1ADORA2AUSP30TRPC3 | |
| SCHEMBL22987791 | 0.93 | TRPC3 (0.33) | ADORA3ADORA1ADORA2AUSP30TRPC3 | |
| SCHEMBL22987599 | 0.93 | TNKS (0.35) | ADORA3ADORA1ADORA2AUSP30TRPC3 | |
| SCHEMBL22987804 | 0.92 | USP30 (0.34) | USP30TRPC3TRPC7PIK3CDJAK2 | |
| SCHEMBL22988240 | 0.92 | ADORA3 (0.35) | ADORA3ADORA1ADORA2AUSP30PIK3CD | |
| SCHEMBL28730362 | 0.92 | ADORA3 (0.35) | ADORA3ADORA1ADORA2AUSP30PIK3CD | |
| SCHEMBL22988171 | 0.92 | ADORA3 (0.35) | ADORA3ADORA1ADORA2AUSP30TRPC3 | |
| SCHEMBL29649011 | 0.92 | ADORA3 (0.35) | ADORA3ADORA1ADORA2AUSP30PIK3CD | |
| SCHEMBL22987467 | 0.92 | NR1H2 (0.35) | ADORA3ADORA1ADORA2AUSP30TRPC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466850-B | [1,2,4] Triazolo [1,5-C ] quinazolin-5-amine | 拜耳股份有限公司 | 2024-09-10 | — | — | CN | disclosed |
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | disclosed |