Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.34 |
| ▸ | TNKS | O95271 | 1/20 | 0.34 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.34 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.33 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.32 |
| ▸ | GPR39 | O43194 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 3/20 | 0.31 |
| ▸ | JAK1 | P23458 | 3/20 | 0.31 |
| ▸ | TYK2 | P29597 | 2/20 | 0.31 |
| ▸ | JAK3 | P52333 | 2/20 | 0.31 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.31 |
| ▸ | LCK | P06239 | 1/20 | 0.31 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22987743 | 1.00 | PARP1 (0.34) | PARP1TNKSTNKS2PARP2PIK3CD | |
| SCHEMBL30392296 | 0.92 | PARP1 (0.33) | PARP1TNKSTNKS2PARP2PIK3CD | |
| SCHEMBL22987755 | 0.92 | PARP1 (0.33) | PARP1TNKSTNKS2PARP2PIK3CD | |
| SCHEMBL22987599 | 0.91 | TNKS (0.35) | PARP1TNKSTNKS2PARP2PIK3CD | |
| SCHEMBL22979177 | 0.91 | CREBBP (0.33) | ADORA3ADORA1ADORA2ABRD4CREBBP | |
| SCHEMBL22988240 | 0.90 | ADORA3 (0.35) | PARP1TNKSTNKS2PARP2PIK3CD | |
| SCHEMBL29649011 | 0.90 | ADORA3 (0.35) | PARP1TNKSTNKS2PARP2PIK3CD | |
| SCHEMBL22987521 | 0.90 | ADORA3 (0.35) | PARP1TNKSTNKS2PARP2PIK3CD | |
| SCHEMBL22988171 | 0.90 | ADORA3 (0.35) | PARP1TNKSTNKS2PARP2PIK3CD | |
| SCHEMBL29646426 | 0.90 | ADORA3 (0.35) | PARP1TNKSTNKS2PARP2PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466850-B | [1,2,4] Triazolo [1,5-C ] quinazolin-5-amine | 拜耳股份有限公司 | 2024-09-10 | — | — | CN | disclosed |
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | disclosed |