Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | HSPB1 | P04792 | 5/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.44 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.43 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | TTR | P02766 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | DHFR | P00374 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21819356 | 1.00 | CYP19A1 (0.52) | CYP19A1ATMTDP1HSPB1AKR1C3 | |
| SCHEMBL16396314 | 0.89 | TDP1 (0.45) | CYP19A1ATMTDP1HSPB1AKR1C3 | |
| SCHEMBL16342390 | 0.89 | TSHR (0.50) | CYP19A1ATMTDP1HSPB1AKR1C3 | |
| SCHEMBL19433252 | 0.89 | TDP1 (0.45) | CYP19A1ATMTDP1HSPB1AKR1C3 | |
| SCHEMBL16402212 | 0.85 | HSPB1 (0.46) | ATMTDP1HSPB1AKR1C3AKR1C2 | |
| SCHEMBL16396032 | 0.85 | VCAM1 (0.54) | CYP19A1ATMTDP1HSPB1AKR1C3 | |
| SCHEMBL30469290 | 0.85 | AKR1C3 (0.60) | ATMTDP1HSPB1AKR1C3AKR1C2 | |
| SCHEMBL20557366 | 0.85 | AKR1C3 (0.60) | ATMTDP1HSPB1AKR1C3AKR1C2 | |
| Fluoride SCHEMBL27401563 | 0.84 | CYP19A1 (0.50) | CYP19A1ATMTDP1HSPB1ALDH1A1 | |
| SCHEMBL16396168 | 0.82 | MAPT (0.49) | ATMTDP1ALDH1A1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115124470-B | Method for preparing sulfonamide structured kinase inhibitors | 奥瑞基尼肿瘤有限公司 | 2024-08-27 | — | — | CN | disclosed |
| EP-4137487-A1 | PROCESS FOR THE PREPARATION OF A SULFONAMIDE STRUCTURED KINASE INHIBITOR | Aurigene Discovery Technologies Limited (IN) | 2023-02-22 | — | — | EP | disclosed |
| EP-3601262-B1 | PROCESS FOR THE PREPARATION OF A SULFONAMIDE STRUCTURED KINASE INHIBITOR | AURIGENE DISCOVERY TECH LTD (IN) | 2022-11-09 | — | — | EP | disclosed |
| US-11332460-B2 | Process for the preparation of a sulfonamide structured kinase inhibitor | ORION CORPORATION (FI) | 2022-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11332460-B2 | Process for the preparation of a sulfonamide structured kinase inhibitor | FGFR1, FGFR2, FGFR4 | CYP19A1 606/4885ATM 631/4885TDP1 1212/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.