Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HB | P07237 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | BLM | P54132 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.51 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.51 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.51 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.51 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.51 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.51 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.51 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.51 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.51 |
| ▸ | PSMA5 | P28066 | 1/20 | 0.51 |
| ▸ | PSMB4 | P28070 | 1/20 | 0.51 |
| ▸ | PSMB6 | P28072 | 1/20 | 0.51 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.51 |
| ▸ | PSMB10 | P40306 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27006536 | 1.00 | P4HB (0.53) | P4HBRAB9AMEN1KMT2ABLM | |
| SCHEMBL27006540 | 0.84 | P4HB (0.50) | P4HBRAB9AMEN1KMT2ABLM | |
| SCHEMBL29647685 | 0.84 | P4HB (0.50) | P4HBRAB9AMEN1KMT2ABLM | |
| SCHEMBL10880347 | 0.84 | CDK4 (0.50) | P4HBRAB9AMEN1KMT2ABLM | |
| SCHEMBL24389188 | 0.84 | MAPT (0.64) | RAB9AMEN1KMT2ABLMNPC1 | |
| SCHEMBL30594065 | 0.84 | MAPT (0.64) | RAB9AMEN1KMT2ABLMNPC1 | |
| SCHEMBL8652779 | 0.83 | CASP3 (0.57) | P4HBRAB9AMEN1KMT2ABLM | |
| SCHEMBL16296903 | 0.81 | MAPT (0.69) | RAB9AMEN1KMT2ABLMNPC1 | |
| SCHEMBL29633276 | 0.81 | MAPT (0.69) | RAB9AMEN1KMT2ABLMNPC1 | |
| SCHEMBL30704424 | 0.79 | MAPT (0.47) | RAB9AMEN1KMT2ABLMNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4232439-A1 | 5-HYDROXY-1,4-NAPHTHALENEDIONE FOR USE IN THE TREATMENT OF CANCER | Godavari Biorefineries Ltd. (IN) | 2023-08-30 | — | — | EP | disclosed |
| CN-116670122-A | 5-hydroxy-1, 4-naphthalenediones for the treatment of cancer | 戈达瓦里生物炼制有限责任公司 | 2023-08-29 | — | — | CN | disclosed |
| WO-2022091123-A1 | 5-HYDROXY-1,4-NAPHTHALENEDIONE FOR USE IN THE TREATMENT OF CANCER | GODAVARI BIOREFINERIES LIMITED (IN) | 2022-05-05 | — | — | WO | disclosed |