SCHEMBL29647873

SCHEMBL29647873

COC(=O)[C@H](CCCNC(N)=O)NC(=O)[C@@H](NC(=O)CCCCCN1C(=O)C=CC1=O)C(C)C

nearest known ligand 0.39

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ FAP Q12884 5/20 0.38
▸ FURIN P09958 5/20 0.38
▸ PRSS1 P07477 1/20 0.37
▸ PTGS1 P23219 4/20 0.36
▸ PTGS2 P35354 4/20 0.36
▸ NPY1R P25929 2/20 0.35
▸ NPY4R P50391 2/20 0.35
▸ NPY5R Q15761 2/20 0.35
▸ NPY2R P49146 1/20 0.35
▸ NMT2 O60551 1/20 0.35
▸ NMT1 P30419 1/20 0.35
▸ HPGD P15428 1/20 0.34
▸ HTT P42858 1/20 0.34
▸ SMN1; SMN2 Q16637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29308956 0.92 NPY5R (0.40) FAPPTGS1PTGS2NPY1RNPY4R
SCHEMBL13078356 0.91 NPY5R (0.38) FAPFURINPTGS1PTGS2NPY1R
SCHEMBL20887736 0.91 FAP (0.37) FAPFURINPTGS1PTGS2NPY1R
SCHEMBL16925642 0.91 C3AR1 (0.40) FAPFURINPTGS1PTGS2NPY1R
SCHEMBL23420959 0.91 FAP (0.37) FAPFURINPTGS1PTGS2NPY1R
SCHEMBL23256221 0.91 NPY5R (0.38) FAPFURINPTGS1PTGS2NPY1R
SCHEMBL19257624 0.91 NPY5R (0.38) FAPFURINPTGS1PTGS2NPY1R
SCHEMBL22134344 0.91 C3AR1 (0.40) FAPFURINPTGS1PTGS2NPY1R
SCHEMBL2801888 0.91 C3AR1 (0.40) FAPFURINPTGS1PTGS2NPY1R
SCHEMBL28051813 0.91 C3AR1 (0.40) FAPFURINPTGS1PTGS2NPY1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12497460-B2 Anti-MSR1 antibodies and methods of use thereof REGENERON PHARMACEUTICALS, INC. (US) 2025-12-16 — — US disclosed
US-20250064954-A1 STEROIDS AND ANTIBODY-CONJUGATES THEREOF REGENERON PHARMACEUTICALS, INC. 2025-02-27 — — US disclosed
US-20240342299-A1 STEROIDS AND ANTIBODY-CONJUGATES THEREOF REGENERON PHARMA (US) 2024-10-17 — — US disclosed
US-12070506-B2 Steroids and antibody-conjugates thereof REGENERON PHARMACEUTICALS, INC. (US) 2024-08-27 — — US disclosed
US-20230079407-A1 ANTI-MSR1 ANTIBODIES AND METHODS OF USE THEREOF REGENERON PHARMACEUTICALS, INC. 2023-03-16 — — US disclosed
US-11377502-B2 Anti-MSR1 antibodies and methods of use thereof REGENERON PHARMACEUTICALS, INC. (US) 2022-07-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240342299-A1 STEROIDS AND ANTIBODY-CONJUGATES THEREOF SERPINA6, NR3C1, NR3C2 FAP 2921/4885FURIN 2386/4885PRSS1 1153/4885
US-12070506-B2 Steroids and antibody-conjugates thereof SERPINA6, NR3C1, NR3C2 FAP 2921/4885FURIN 2386/4885PRSS1 1153/4885
US-20230079407-A1 ANTI-MSR1 ANTIBODIES AND METHODS OF USE THEREOF CD47, MSR1, LDLR FAP 4480/4885FURIN 2044/4885PRSS1 1064/4885
US-20250064954-A1 STEROIDS AND ANTIBODY-CONJUGATES THEREOF SERPINA6, NR3C1, NR3C2 FAP 2921/4885FURIN 2386/4885PRSS1 1153/4885
US-12497460-B2 Anti-MSR1 antibodies and methods of use thereof CD47, MSR1, LDLR FAP 4480/4885FURIN 2044/4885PRSS1 1064/4885
US-11377502-B2 Anti-MSR1 antibodies and methods of use thereof CD47, MSR1, LDLR FAP 4480/4885FURIN 2044/4885PRSS1 1064/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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