Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.34 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.34 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.33 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.33 |
| ▸ | SUV39H1 | O43463 | 3/20 | 0.32 |
| ▸ | PRMT1 | Q99873 | 3/20 | 0.32 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.32 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6332114 | 0.80 | PDE4A (0.47) | PDE4APDE4BPDE4CPDE4DMAP4K4 | |
| SCHEMBL4968804 | 0.80 | PDE4A (0.47) | PDE4APDE4BPDE4CPDE4DCSNK2A1 | |
| SCHEMBL6843232 | 0.78 | PDE4A (0.46) | PDE4APDE4BPDE4CPDE4DSLC22A12 | |
| Hydrochloric Acid SCHEMBL6332115 | 0.78 | PDE4A (0.46) | PDE4APDE4BPDE4CPDE4DCSNK2A1 | |
| SCHEMBL694117 | 0.75 | CSNK2A1 (0.57) | PDE4APDE4BPDE4CPDE4DCSNK2A1 | |
| SCHEMBL29648005 | 0.72 | EGFR (0.50) | CSNK2A1CSNK2A2CSNK2BEGFR | |
| SCHEMBL6323082 | 0.71 | HPGD (0.52) | POLBSMYD3MEN1MAPTMAPK1 | |
| SCHEMBL6331446 | 0.71 | PLA2G7 (0.43) | PDE4APDE4BPDE4CPDE4DSLC22A12 | |
| SCHEMBL6332625 | 0.71 | HPGD (0.52) | MEN1MAPTKMT2A | |
| SCHEMBL4150819 | 0.71 | HPGD (0.56) | POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3999498-A1 | INHIBITORS OF CYCLIN-DEPENDENT KINASES | Kinnate Biopharma Inc. (US) | 2022-05-25 | — | — | EP | disclosed |